Chan Zuckerberg Biohub Inc

Organization Overview

Chan Zuckerberg Biohub Inc is located in San Francisco, CA. The organization was established in 2016. According to its NTEE Classification (H99) the organization is classified as: Medical Research N.E.C., under the broad grouping of Medical Research and related organizations. As of 12/2021, Chan Zuckerberg Biohub Inc employed 167 individuals. This organization is an independent organization and not affiliated with a larger national or regional group of organizations. Chan Zuckerberg Biohub Inc is a 501(c)(3) and as such, is described as a "Charitable or Religous organization or a private foundation" by the IRS.

For the year ending 12/2021, Chan Zuckerberg Biohub Inc generated $10.3m in total revenue. This represents a relatively dramatic decline in revenue. Over the past 6 years, the organization has seen revenues fall by an average of (48.9%) each year. All expenses for the organization totaled $73.8m during the year ending 12/2021. You can explore the organizations financials more deeply in the financial statements section below.

Since 2016, Chan Zuckerberg Biohub Inc has awarded 19 individual grants totaling $114,311,932. If you would like to learn more about the grant giving history of this organization, scroll down to the grant profile section of this page.

Mission & Program ActivityExcerpts From the 990 Filing

TAX YEAR

2021

Describe the Organization's Mission:

Part 3 - Line 1

CONDUCT CUTTING EDGE MEDICAL RESEARCH

Describe the Organization's Program Activity:

Part 3 - Line 4a

IN 2021 THE CHAN ZUCKERBERG BIOHUB, INC. ("CZ BIOHUB") CELEBRATED ITS 5TH ANNIVERSARY AS A MEDICAL RESEARCH ORGANIZATION. CONSISTENT WITH OUR MISSION, WE CONTINUED TO FOCUS ON LARGE-SCALE SCIENTIFIC INITIATIVES THAT WE ARE UNIQUELY POSITIONED TO SUPPORT AND EXECUTE, EACH ON A MULTI-YEAR TIMELINE:1. INTRAMURAL RESEARCH PROJECTS LED BY CZ BIOHUB RESEARCHERS THAT EMPHASIZE BASIC SCIENCE, IN TWO MAIN AREAS:A. QUANTITATIVE CELL SCIENCEB. INFECTIOUS DISEASE2. RESEARCH PROJECTS CARRIED OUT BY SCIENTISTS AT OUR PARTNER UNIVERSITIES (STANFORD UNIVERSITY; UC SAN FRANCISCO; UC BERKELEY) WITH THE BACKING OF THE CZ BIOHUB INVESTIGATOR PROGRAM.IN 2021, CZ BIOHUB RESEARCHERS AND INVESTIGATORS WERE AUTHORS OF 173 SCIENTIFIC PUBLICATIONS AND PREPRINTS.QUANTITATIVE CELL SCIENCE HIGHLIGHTS THE WEBSITE FOR OPENCELL, AN OPEN-SOURCE, PROTEOME-SCALE COLLECTION OF PROTEIN LOCALIZATION AND INTERACTION MEASUREMENTS IN HUMAN CELLS, WAS LAUNCHED. A MANUSCRIPT DESCRIBING OPENCELL METHODS AND DATA WAS PLACED ON TO THE BIORXIV PREPRINT SERVER AND HAS SINCE BEEN DOWNLOADED >10,000 TIMES, PLACING THE PAPER IN THE TOP 5% OF ALL RESEARCH TRACKED BY ALTMETRIC. (THE OPENCELL PAPER WAS PUBLISHED IN SCIENCE IN MARCH 2022.) THE MANUSCRIPT FOR TABULA SAPIENS, A HUMAN CELL ATLAS BASED ON SINGLE-CELL RNA SEQUENCING AND HISTOLOGY OF NEARLY 500,000 CELLS IN 24 ORGANS FROM 15 DONORS, WAS UPLOADED TO THE BIORXIV PREPRINT SERVER, AND THE COMPLETE, OPEN-SOURCE TABULA SAPIENS DATASET WAS RELEASED. THE MANUSCRIPT HAS BEEN DOWNLOADED >9,000 TIMES, ALSO RANKING IN THE TOP 5% OF ALL RESEARCH TRACKED BY ALTMETRIC. (THE TABULA SAPIENS PAPER WAS PUBLISHED IN SCIENCE IN MAY 2022.)INFECTIOUS DISEASE HIGHLIGHTS IN COLLABORATION WITH THE CHAN ZUCKERBERG INITIATIVE (CZI), OUR INFECTIOUS DISEASE RESEARCHERS AND GENOMICS AND DATA SCIENCE TEAMS CREATED THE CALIFORNIA COVID TRACKER (CZ GEN EPI), A WEB PORTAL AND DATABASE TO IDENTIFY AND TRACK SARS-COV-2 LINEAGES AND VARIANTS. IN CELL IN JANUARY 2021, CZ BIOHUB RESEARCHERS AND INVESTIGATORS REPORTED THAT A WHOLE-GENOME SCREEN REVEALED HOST-CELL FACTORS REQUIRED FOR INFECTION BY SARS-COV-2 AND RELATED CORONAVIRUSES; THESE HOST FACTORS ARE POTENTIAL THERAPEUTIC TARGETS IN COVID AND OTHER RESPIRATORY VIRAL DISEASES.INVESTIGATOR PROGRAM HIGHLIGHTSTHE BIOHUB ESTABLISHED ITS SECOND COHORT OF CZ BIOHUB INVESTIGATORS, MADE UP OF 86 LEADING SCIENTISTS WORKING IN DIVERSE DISCIPLINES AT OUR THREE PARTNER UNIVERSITIES. THE NEW INVESTIGATORS WERE CHOSEN FROM A POOL OF NEARLY 700 APPLICANTS IN A COMPETITIVE PROCESS JUDGED BY NATIONALLY RECOGNIZED EXTERNAL REVIEWERS AND A BLUE-RIBBON SELECTION ADVISORY COMMITTEE.


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Board, Officers & Key Employees

Name (title)Compensation
Steve Quake
Co-President
$836,921
Joseph Derisi
Co-President
$836,621
Gajus Worthington
Chief Operating Officer
$681,698
Victor Colunga
CFO & Treasurer
$648,222
Sandra L Schmid
Chief Scientific Officer
$562,983
Jim Karkanias
Chief Technology Officer
$524,041

Outside Vendors & Contractors

Vendor Name (Service)Compensation
Kdinfotech
It Services
$559,737
Arnold & Porter Kaye Scholer Llp
Legal Services
$1,132,801
Nexus Contingent Workforce
Temporary Services
$457,732
Marshall Gerstein & Borun Llp
Legal Services
$466,820
Kilpatrick Townsend
Legal Services
$1,044,597
View All Vendors

Financial Statements

Statement of Revenue
Federated campaigns$0
Membership dues$0
Fundraising events$0
Related organizations$2,195,983
Government grants $0
All other contributions, gifts, grants, and similar amounts not included above$6,443,757
Noncash contributions included in lines 1a–1f $774,511
Total Revenue from Contributions, Gifts, Grants & Similar$8,639,740
Total Program Service Revenue$1,356,240
Investment income $34,766
Tax Exempt Bond Proceeds $0
Royalties $284,009
Net Rental Income $0
Net Gain/Loss on Asset Sales $0
Net Income from Fundraising Events $0
Net Income from Gaming Activities $0
Net Income from Sales of Inventory $0
Miscellaneous Revenue$0
Total Revenue $10,314,755

Grants Awarded

Over the last fiscal year, Chan Zuckerberg Biohub Inc has awarded $21,070,869 in support to 3 organizations.

Grant RecipientAmount

San Francisco, CA

PURPOSE: SCIENTIFIC AND MEDICAL RESEARCH

$8,528,162

STANFORD UNIVERSITY

Org PageRecipient Profile

Redwood City, CA

PURPOSE: SCIENTIFIC AND MEDICAL RESEARCH

$8,442,707

Berkeley, CA

PURPOSE: SCIENTIFIC AND MEDICAL RESEARCH

$4,100,000
View Grant Profile

Grants Recieved

Over the last fiscal year, we have identified 4 grants that Chan Zuckerberg Biohub Inc has recieved totaling $65,411,883.

Awarding OrganizationAmount
Chan Zuckerberg Initiative Foundation

Palo Alto, CA

PURPOSE: MEDICAL RESEARCH

$60,000,000
Chan Zuckerberg Initiative Foundation

Palo Alto, CA

PURPOSE: MEDICAL RESEARCH

$2,195,983
Aphorism Foundation

San Francisco, CA

PURPOSE: GENERAL SUPPORT

$2,000,000
Silicon Valley Community Foundation

Mountain View, CA

PURPOSE: Health

$1,215,900
View Grant Recipient Profile

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