Clinton Health Access Initiative Inc

THE CLINTON HEALTH ACCESS INITIATIVE, INC. (CHAI) IS A GLOBAL HEALTH ORGANIZATION COMMITTED TO SAVING LIVES AND REDUCING THE BURDEN OF DISEASE IN LOW- AND MIDDLE-INCOME COUNTRIES.

OUR PROGRAMS AIM TO SAVE LIVES AND REDUCE THE BURDEN OF DISEASE, WHILE HELPING GOVERNMENTS CREATE SUSTAINABLE HEALTH SYSTEMS. WE OPERATE IN OVER 35 COUNTRIES WITH 20 PROGRAMS ACROSS FOUR HEALTH AREAS. THE VAST MAJORITY OF OUR STAFF ARE LOCATED IN THE COUNTRIES WHERE WE WORK, OVERSEEING IMPLEMENTATION AND MANAGING RELATIONSHIPS WITH PARTNER GOVERNMENTS. THE TEAMS ON THE GROUND ARE COMPLEMENTED BY A GLOBAL TEAM OF SCIENCE, BUSINESS, AND TECHNICAL EXPERTS SUPPORTING THE ENTIRE ORGANIZATION AND BY MANAGEMENT, FINANCE, AND HUMAN RESOURCE TEAMS. INFECTIOUS DISEASES: SEE SCHEDULE O FOR CONTINUATIONINFECTIOUS DISEASES: FOR YEARS, FOUR INFECTIOUS DISEASES DROVE MOST ILLNESS AND DEATH WORLDWIDE: HIV, HEPATITIS, TUBERCUOSIS (TB), AND MALARIA. IN 2020, A NEW ILLNESS, COVID-19 OVERTOOK THESE DISEASES AS THE LARGEST CAUSE OF GLOBAL MORTALITY BY AN INFECTIOUS DISEASE.EARLY ON, THE PANDEMIC BROUGHT MANY HEALTH SYSTEMS TO THEIR KNEES, AND IT CONTINUES TO EXPOSE AND EXACERBATE INEQUITIES THAT ALREADY EXISTED BETWEEN COUNTRIES, PEOPLE, AND ACCESS TO BASIC HEALTH SERVICES. IN 2021, CHAI CONTINUED TO PLAY A LEADING ROLE GLOBALLY AND IN COUNTRIES TO GUIDE A RAPID RESPONSE TO COVID-19. AT THE GLOBAL LEVEL, CHAI WORKED WITH SUPPLIERS TO SECURE ALLOCATIONS OF COVID-19 ANTIGEN TESTS FOR LOW- AND MIDDLE-INCOME COUNTRIES AT AFFORDABLE PRICES OF LESS THAN US$3.50 AND ENABLE CATALYTIC DONATION OF THE TEST KITS TO OVER 15 HIGH-BURDEN COUNTRIES. ADDITIONALLY, WE SUPPORTED THE DEVLEPOMENT OF TESTING GUIDANCE AND TOOLS, PROVIDED INPUT ON TESTING TECHNOLOGIES, AND SHARED LESSONS FROM OUR IMPLEMENTATION EXPERIENCE TO INFORM INVESTMENTS OF VARIOUS PARTNERS, INCLUDING THE WHO-LED DIAGNOSTICS SUPPLY CONSORTIUM, THE ACT-ACCELERATOR FOR DIAGNOSTICS, THE AFRICA CDC-LED PARTNERSHIP TO ACCELERATE COVID-19 TESTING (PACT) INITIATIVE, AND THE GLOBAL FUND. IN COUNTRIES, CHAI CATALYZED THE INTRODUCTION AND SCALEUP OF COVID-19 TESTING SERVICES BY ESTABLISHING KEY ENABLING CONDITIONS SECURING MINISTRY OF HEALTH BUY-IN, UPDATING POLICIES AND STRATEGIES, ESTABLISHING SUPPLY CHAINS, AND TRAINING. WE EXPANDED COVID-19 TESTING CAPACITY AND HELPED BUILD A DIAGNOSTICS NETWORK THAT MAXIMIZES TESTING COVERAGE AND REFERRAL TO CARE. TAKEN TOGETHER, CHAI'S GLOBAL AND COUNTRY EFFORTS CATALYZED THE PROCUREMENT OF MORE THAN 31.9 MILLION ANTIGEN TESTS, PLAYING A CRITICAL ROLE IN EFFORTS TO COMBAT THE PANDEMIC.CHAI WAS FOUNDED TO SAVE THE LIVES OF MILLIONS OF PEOPLE LIVING WITH HIV/AIDS. TODAY OVER 21 MILLION PEOPLE LIVING WITH HIV ARE RECEIVING TREATMENT, MAKING IT A CHRONIC ILLNESS INSTEAD OF A DEATH SENTENCE. OVER 900,000 CHILDREN ARE RECEVING TREATMENT, FROM LESS THAN 100,000 WHEN CHAI'S WORK BEGAN, AND THE COST OF MEDICATIONS HAS FALLEN SIGNIFCANTLY. BUILDING ON A HISTORIC LANDMARK PRICING AGREEMENT AND TENTATIVE APPROVAL OF PEDIATRIC DOLUTEGRAVIR (DTG) BY THE U.S. FOOD AND DRUG ADMINISTRATION, CHAI WORKED WITH MINISTRIES OF HEALTH IN 2021 TO ACHIEVE RAPID ADOPTION AND TRANSITION FROM LESS OPTIMAL PEDIATRIC REGIMENS.IN ADDITION, CHAI'S EFFORTS TO TRACK AND TREAT MALARIA CASES, WITH THE GOAL OF ELMINATION, HAS HELPED LEAD TO SIGNIFICANT DECLINES IN MALARIA PREVALENCE. CHAI HAS HELPED TO SIGNIFICANTLY REDUCE THE COSTS OF LIFESAVING TREATMENTS FOR TB AND HEPATITIS AND CONTINUES SUPPORT FOR SEVERAL COUNTRIES' PLANS TO RAPIDLY ELIMINATE HEPATITIS C.

WOMEN & CHILDREN'S HEALTH: SEE SCHEDULE O FOR CONTINUATIONWOMEN & CHILDREN'S HEALTH: WWOMEN AND CHILDREN SUFFER THE GREATEST BURDEN FROM DISEASE GLOBALLY. CHAI HAS SIGNIFICANTLY INCREASED ACCESS TO RECOMMENDED TREATMENTS FOR DIARRHEA AND PNEUMONIA, THE LARGEST KILLERS OF CHILDREN UNDER FIVE; MADE CRITICAL VACCINES THAT PROTECT AGAINST CHILDHOOD ILLNESSES MORE AFFORDABLE; IS COMBATTING CHRONIC MALNUTRITION; AND IS DRAMATIALLY AND SUSTAINABLY REDUCING MATERNAL AND NEWBORN DEATHS AND ENSURING WOMEN HAVE ACCESS TO THE TOOLS THEY NEED TO SAFELY PLAN THER FAMILIES TO IMPROVE HEALTH OUTCOMES AND ECONOMIC WELLBEING.THROUGH THIS WORK, CHAI HAS SIGNIFICANTLY INCREASED ACCESS TO LIFESAVING TREATMENTS FOR DIARRHEA (ZINC AND ORAL REHYDRATION SALTS) AND PNEUMONIA (INCLUDING OPTIMAL MEDICATIONS AND OXYGEN THERAPY), AS WELL AS TOOLS FOR DIAGNOSIS. CHAI'S WORK TO SAVE THE LIVES OF WOMEN AND NEWBORNS THROUGH INTEGRATING HEALTH SYSTEMS AND INCREASING ACCESS TO LIFESAVING CARE HAS CONTRIBUTED TO SUSTAINED AND SIGNFICANT REDUCTIONS IN DEATH IN COUNTRIES WHERE WE WORK, INCLUDING A NEARLY 40 PERCENT REDUCTION IN MATERNAL MORTALITY AND A 43 PERCENT REDUCTION IN NEWBORN DEATHS IN A 12- MONTH PERIOD IN TARGET STATES OF NORTHERN NIGERIA. CHAI HAS ALSO HELPED TO SIGNIFICANTLY LOWER THE COST OF LIFESAVING MEDICAL EQUIPMENT AND FAMILY PLANNING TO SAVE THE LIVES OF WOMEN. CHAI IS HELPING GOVERMENTS DECREASE CHRONIC MALNUTRITION THROUGH DEVELOPMENT OF LOCALLY BASED, FORTIFIED FOODS, IMPROVING NUTRITION PROGRAMS, AND REDUCING ANEMIA. IN RWANDA, FROM 2017 TO 2021, THIS WORK HAS RESULTED IN CHILDREN LIVING IN THE POOREST HOUSEHOLDS HAVING A 41 PERCENT REDUCTION IN THE ODDS OF BEING STUNTED AND A 33 PERCENT REDUCTION IN THE ODDS OF BEING UNDERWEIGHT. CHAI HAS ALSO SIGNIFICANTLY DECREASED THE COSTS OF LIFESAVING CHILDHOOD VACCINATIONS, IMPROVED VACCINE COLD CHAINS, LOGISTICS SYSTEMS, AND SERVICE DELIVERY TO INCREASE EFFECTIVE, AFFORDABLE IMMUNIZATION COVERAGE FOR ALL.

NON-COMMUNICABLE DISEASES: SEE SCHEDULE O FOR CONTINUATIONNON-COMMUNICABLE DISEASES: NON-COMMUNICABLE DISEASES (NCDS) SUCH AS HEART DISEASE, CANCER, CHRONIC RESPIRATORY DISEASE, AND DIABETES ARE THE LEADING CAUSE OF DEATH GLOBALLY, EXCEEDING ALL COMMUNICABLE DISEASE DEATHS COMBINED. DEATHS FROM NCDS IN LOW- AND MIDDLE-INCOME COUNTRIES ACCOUNT FOR AT LEAST 77 PERCENT OF ALL DEATHS GLOBALLY.CHAI WORKS WITH THE AMERICAN CANCER SOCIETY AND OTHER PARTNERS TO LOWER THE COST OF LIFESAVING CHEMOTHERAPIES, INCREASE ACCESS TO DIAGNOSIS AND TREATMENT, AND HELP GOVERNMENTS DEVELOP PLANS TO COMPREHENSIVELY MANAGE CANCERS. CHAI'S WORK HAS HELPED LOWER THE COST OF TREATMENT FOR 30 CANCERS, INCLUDING BREAST CANCER THE MOST COMMONLY DIAGNOSED CANCER GLOBALLY WHICH IS EXPECTED TO GENERATE SAVINGS OF 60 PERCENT ON PURCHASED MEDICATIONS. CHAI ALSO SUPPORTS GLOBAL EFFORTS TO ELIMINATE CERVICAL CANCER BY HELPING TO SUBSTANTIALLY INCREASE THE NUMBER OF WOMEN SCREENED FOR PRECANCEROUS LESIONS AND APPROPRIATELY TREATED.TO ADDRESS THE INCREASING PREVALENCE OF NCDS IN PARTNER COUNTRIES, CHAI IS WORKING WITH GOVERNMENTS TO INTEGRATE TESTING WHERE POSSIBLE. IN ESWATINI, 40 PERCENT OF ADULTS OVER 40 WHO ARE ON HIV TREATMENT ARE AT RISK OF CARDIOVASCULAR DISEASE, WHILE A QUARTER HAVE HYPERTENSION. WORKING WITH THE MINISTRY OF HEALTH, CHAI QUICKLY INTEGRATED NCD AND HIV SERVICES. SIMILARLY, IN CAMBODIA, WHERE THE PREVALANCE OF DIABETES IS HIGH, A PILOT PROGRAM WAS INTRODUCED TO PROVIDE ADULTS OVER 40 WITH DIABETES AND HYPERTENSION SCREENING WHILE THEY RECEIVED COVID-19 VACCINATIONS.